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ADPKD in humans causes damage primarily to the proximal tubule while polycystic models demonstrate damage primarily to the distal tubule

Marc Klaas to close foundation 3 decades after daughter, Polly, killed in Petaluma After 30 years of searching for America's lost and missing children inspired by the kidnap and murder of his own 12-year-old daughter, Polly Marc Klaas said he's finally shutting down the Sausalito-based KlaasKids Foundation